Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?

[Image: see text] The activation of PINK1 by small molecules has emerged as a promising strategy in treating Parkinson’s disease (PD). Recent progress in this area has raised excitement around PINK1 activators as PD treatments, and herein we offer insight into these developments and their potential...

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Detalles Bibliográficos
Autor principal: Mehellou, Youcef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350934/
https://www.ncbi.nlm.nih.gov/pubmed/37465300
http://dx.doi.org/10.1021/acsmedchemlett.3c00070
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author Mehellou, Youcef
author_facet Mehellou, Youcef
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description [Image: see text] The activation of PINK1 by small molecules has emerged as a promising strategy in treating Parkinson’s disease (PD). Recent progress in this area has raised excitement around PINK1 activators as PD treatments, and herein we offer insight into these developments and their potential to deliver much needed novel PD treatments.
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spelling pubmed-103509342023-07-18 Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic? Mehellou, Youcef ACS Med Chem Lett [Image: see text] The activation of PINK1 by small molecules has emerged as a promising strategy in treating Parkinson’s disease (PD). Recent progress in this area has raised excitement around PINK1 activators as PD treatments, and herein we offer insight into these developments and their potential to deliver much needed novel PD treatments. American Chemical Society 2023-06-15 /pmc/articles/PMC10350934/ /pubmed/37465300 http://dx.doi.org/10.1021/acsmedchemlett.3c00070 Text en © 2023 The Author. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Mehellou, Youcef
Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
title Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
title_full Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
title_fullStr Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
title_full_unstemmed Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
title_short Parkinson’s Disease: Are PINK1 Activators Inching Closer to the Clinic?
title_sort parkinson’s disease: are pink1 activators inching closer to the clinic?
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10350934/
https://www.ncbi.nlm.nih.gov/pubmed/37465300
http://dx.doi.org/10.1021/acsmedchemlett.3c00070
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