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Anti-infectives Developed as Racemic Drugs in the 21st Century: Norm or Exception?
[Image: see text] This viewpoint outlines the case for developing new chemical entities (NCEs) as racemates in infectious diseases and where both enantiomers and racemate retain similar on- and off-target activities as well as similar PK profiles. There are not major regulatory impediments for the d...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351050/ https://www.ncbi.nlm.nih.gov/pubmed/37465315 http://dx.doi.org/10.1021/acsmedchemlett.3c00214 |