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Double protection in patients with a massive thrombus in the infarct-related artery – a single-center retrospective study

INTRODUCTION: ST-segment elevation myocardial infarction (STEMI) is associated with thrombus formation on a ruptured or ulcerated atherosclerotic plaque. The consequences of a massive thrombus (MT) may include lack of reperfusion, extensive myocardial infarction (MI) and its complications. Although...

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Detalles Bibliográficos
Autores principales: Chodór, Piotr, Honisz, Grzegorz, Wilczek, Krzysztof, Świerad, Marcin, Chodór-Rozwadowska, Karolina, Kalarus, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351081/
https://www.ncbi.nlm.nih.gov/pubmed/37465636
http://dx.doi.org/10.5114/aic.2023.129211
Descripción
Sumario:INTRODUCTION: ST-segment elevation myocardial infarction (STEMI) is associated with thrombus formation on a ruptured or ulcerated atherosclerotic plaque. The consequences of a massive thrombus (MT) may include lack of reperfusion, extensive myocardial infarction (MI) and its complications. Although there are various treatment options for patients with coronary thrombi, double protection (DP) – manual thrombectomy (MTH) with a distal protection device (DPD) – has not been tested yet. AIM: To present DP outcomes in the treatment of patients with STEMI and MT patients. MATERIAL AND METHODS: Fourteen patients with STEMI and MT were included in the study. Those patients underwent primary percutaneous coronary intervention (PPCI) with DP. RESULTS: Inferior MI was found in 12 (85.8%) patients. Stents were implanted in 13 (92.8%) patients. Thrombolysis In Myocardial Infarction (TIMI) Thrombus Grade 5 was present in 11 (78.6%) patients and Grade 4 in 3 (21.4%) patients. The median thrombus length was 39.1 mm. Complete reperfusion (TIMI flow 3) was observed in 11 (78.6%) patients and TIMI flow 2 in 3 (21.4%) patients. Myocardial Blush Grade (MBG) was used in patients with TIMI flow 3 and Grade 3 was found in 5 (35.7%) patients. Resolution in ST-segment elevation > 50% was obtained in 13 (92.8%) patients. No myocardial rupture, stroke, or death occurred during hospitalization. CONCLUSIONS: DP in MT patients is a safe and feasible procedure. However, further observations and studies are needed to assess the efficacy of this method.