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Spatially resolved, high-dimensional transcriptomics sorts out the evolution of biphasic malignant pleural mesothelioma: new paradigms for immunotherapy

BACKGROUND: Malignant Pleural Mesothelioma (MPM) is a dreadful disease escaping the classical genetic model of cancer evolution and characterized by wide heterogeneity and transcriptional plasticity. Clinical evolution of MPM is marked by a progressive transdifferentiation that converts well differe...

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Detalles Bibliográficos
Autores principales:	Torricelli, F, Donati, B, Reggiani, F, Manicardi, V, Piana, S, Valli, R, Lococo, F, Ciarrocchi, Alessia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351128/ https://www.ncbi.nlm.nih.gov/pubmed/37460925 http://dx.doi.org/10.1186/s12943-023-01816-9

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