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Dual Recombinase–Based Mouse Models Help Decipher Cancer Biology and Targets for Therapy

The advent of next-generation sequencing (NGS) and single-cell profiling technologies has revealed the complex and heterogenous ecosystem of human tumors under steady-state and therapeutic perturbation. Breakthroughs in the development of genetically engineered mouse models (GEMM) of human cancers t...

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Detalles Bibliográficos
Autores principales: Sket, Tina, Falcomatà, Chiara, Saur, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351565/
https://www.ncbi.nlm.nih.gov/pubmed/37449355
http://dx.doi.org/10.1158/0008-5472.CAN-22-2119