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Dual Recombinase–Based Mouse Models Help Decipher Cancer Biology and Targets for Therapy
The advent of next-generation sequencing (NGS) and single-cell profiling technologies has revealed the complex and heterogenous ecosystem of human tumors under steady-state and therapeutic perturbation. Breakthroughs in the development of genetically engineered mouse models (GEMM) of human cancers t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351565/ https://www.ncbi.nlm.nih.gov/pubmed/37449355 http://dx.doi.org/10.1158/0008-5472.CAN-22-2119 |