DAPTEV: Deep aptamer evolutionary modelling for COVID-19 drug design

Typical drug discovery and development processes are costly, time consuming and often biased by expert opinion. Aptamers are short, single-stranded oligonucleotides (RNA/DNA) that bind to target proteins and other types of biomolecules. Compared with small-molecule drugs, aptamers can bind to their...

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Detalles Bibliográficos
Autores principales: Andress, Cameron, Kappel, Kalli, Villena, Marcus Elbert, Cuperlovic-Culf, Miroslava, Yan, Hongbin, Li, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351721/
https://www.ncbi.nlm.nih.gov/pubmed/37406007
http://dx.doi.org/10.1371/journal.pcbi.1010774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351721/
https://www.ncbi.nlm.nih.gov/pubmed/37406007
http://dx.doi.org/10.1371/journal.pcbi.1010774

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