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DAPTEV: Deep aptamer evolutionary modelling for COVID-19 drug design
Typical drug discovery and development processes are costly, time consuming and often biased by expert opinion. Aptamers are short, single-stranded oligonucleotides (RNA/DNA) that bind to target proteins and other types of biomolecules. Compared with small-molecule drugs, aptamers can bind to their...
Autores principales: | Andress, Cameron, Kappel, Kalli, Villena, Marcus Elbert, Cuperlovic-Culf, Miroslava, Yan, Hongbin, Li, Yifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351721/ https://www.ncbi.nlm.nih.gov/pubmed/37406007 http://dx.doi.org/10.1371/journal.pcbi.1010774 |
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