Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool

Human epidermal growth factor receptor-2 (HER2) is a well-recognised biomarker associated with 25% of breast cancers. In most cases, early detection and/or treatment correlates with an increased chance of survival. This study, has identified and characterised a highly specific anti-HER2 single-domai...

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Detalles Bibliográficos
Autores principales: Sawmynaden, Kovilen, Wong, Nicholas, Davies, Sarah, Cowan, Richard, Brown, Richard, Tang, David, Henry, Maud, Tickle, David, Matthews, David, Carr, Mark, Bakrania, Preeti, Hoi Ting, Hong, Hall, Gareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351726/
https://www.ncbi.nlm.nih.gov/pubmed/37459326
http://dx.doi.org/10.1371/journal.pone.0288259

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