Cargando…
Mouse nuclear RNAi-defective 2 promotes splicing of weak 5′ splice sites
Removal of introns during pre-mRNA splicing, which is central to gene expression, initiates by base pairing of U1 snRNA with a 5′ splice site (5′SS). In mammals, many introns contain weak 5′SSs that are not efficiently recognized by the canonical U1 snRNP, suggesting alternative mechanisms exist. He...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351895/ https://www.ncbi.nlm.nih.gov/pubmed/37137667 http://dx.doi.org/10.1261/rna.079465.122 |