Baseline serum HBV RNA is associated with the risk of hepatitis flare after stopping nucleoside analog therapy in HBeAg-negative participants

HBV RNA in peripheral blood reflects HBV cccDNA transcriptional activity and may predict clinical outcomes. The prospective Melbourne HBV-STOP trial studied nucleot(s)ide analog discontinuation in HBeAg-negative non-cirrhotic participants with long-term virological suppression. Ninety-six weeks afte...

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Detalles Bibliográficos
Autores principales: Thompson, Alexander J., Jackson, Kathy, Bonanzinga, Sara, Hall, Sam A.L., Hume, Simon, Burns, Gareth S., Sundararajan, Vijaya, Ratnam, Dilip, Levy, Miriam T., Lubel, John, Nicoll, Amanda J., Strasser, Simone I., Sievert, William, Desmond, Paul V., Ngu, Meng C., Sinclair, Marie, Meredith, Christopher, Matthews, Gail, Revill, Peter A., Littlejohn, Margaret, Bowden, D. Scott, Canchola, Jesse A., Torres, Jason, Siew, Philip, Lau, Jasmin, La Brot, Benjamin, Kuchta, Alison, Visvanathan, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10351945/
https://www.ncbi.nlm.nih.gov/pubmed/37459199
http://dx.doi.org/10.1097/HC9.0000000000000188

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