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Regulation of Schwann cell proliferation and migration via miR-195-5p-induced Crebl2 downregulation upon peripheral nerve damage

BACKGROUND: Schwann cells acquire a repair phenotype upon peripheral nerve injury (PNI), generating an optimal microenvironment that drives nerve repair. Multiple microRNAs (miRNAs) show differential expression in the damaged peripheral nerve, with critical regulatory functions in Schwann cell featu...

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Detalles Bibliográficos
Autores principales: Li, Shiying, Wu, Wenshuang, Zhang, Jing, Chen, Yu, Wu, Yumeng, Wang, Xinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352107/
https://www.ncbi.nlm.nih.gov/pubmed/37469605
http://dx.doi.org/10.3389/fncel.2023.1173086