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Glutamate spillover drives robust all-or-none dendritic plateau potentials—an in silico investigation using models of striatal projection neurons

Plateau potentials are a critical feature of neuronal excitability, but their all-or-none behavior is not easily captured in modeling. In this study, we investigated models of plateau potentials in multi-compartment neuron models and found that including glutamate spillover provides robust all-or-no...

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Detalles Bibliográficos
Autores principales: Trpevski, Daniel, Khodadadi, Zahra, Carannante, Ilaria, Hellgren Kotaleski, Jeanette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352111/
https://www.ncbi.nlm.nih.gov/pubmed/37469606
http://dx.doi.org/10.3389/fncel.2023.1196182