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Glutamate spillover drives robust all-or-none dendritic plateau potentials—an in silico investigation using models of striatal projection neurons
Plateau potentials are a critical feature of neuronal excitability, but their all-or-none behavior is not easily captured in modeling. In this study, we investigated models of plateau potentials in multi-compartment neuron models and found that including glutamate spillover provides robust all-or-no...
Autores principales: | Trpevski, Daniel, Khodadadi, Zahra, Carannante, Ilaria, Hellgren Kotaleski, Jeanette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352111/ https://www.ncbi.nlm.nih.gov/pubmed/37469606 http://dx.doi.org/10.3389/fncel.2023.1196182 |
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