Readout of histone methylation by Trim24 locally restricts chromatin opening by p53

The genomic binding sites of the transcription factor (TF) and tumor suppressor p53 are unusually diverse with regard to their chromatin features, including histone modifications, raising the possibility that the local chromatin environment can contextualize p53 regulation. Here, we show that epigen...

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Detalles Bibliográficos
Autores principales: Isbel, Luke, Iskar, Murat, Durdu, Sevi, Weiss, Joscha, Grand, Ralph S., Hietter-Pfeiffer, Eric, Kozicka, Zuzanna, Michael, Alicia K., Burger, Lukas, Thomä, Nicolas H., Schübeler, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352137/
https://www.ncbi.nlm.nih.gov/pubmed/37386214
http://dx.doi.org/10.1038/s41594-023-01021-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352137/
https://www.ncbi.nlm.nih.gov/pubmed/37386214
http://dx.doi.org/10.1038/s41594-023-01021-8

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