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Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
The genomic binding sites of the transcription factor (TF) and tumor suppressor p53 are unusually diverse with regard to their chromatin features, including histone modifications, raising the possibility that the local chromatin environment can contextualize p53 regulation. Here, we show that epigen...
Autores principales: | Isbel, Luke, Iskar, Murat, Durdu, Sevi, Weiss, Joscha, Grand, Ralph S., Hietter-Pfeiffer, Eric, Kozicka, Zuzanna, Michael, Alicia K., Burger, Lukas, Thomä, Nicolas H., Schübeler, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352137/ https://www.ncbi.nlm.nih.gov/pubmed/37386214 http://dx.doi.org/10.1038/s41594-023-01021-8 |
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