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In vivo effects of the alpha-synuclein misfolding inhibitor minzasolmin supports clinical development in Parkinson’s disease

Direct targeting of alpha-synuclein (ASYN) has emerged as a disease-modifying strategy for Parkinson’s disease and other synucleinopathies which is being approached using both small molecule compounds and ASYN-targeted biologics. Minzasolmin (UCB0599) is an orally bioavailable and brain-penetrant sm...

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Detalles Bibliográficos
Autores principales:	Price, Diana L., Khan, Asma, Angers, Rachel, Cardenas, Alvaro, Prato, Maria Key, Bani, Massimo, Bonhaus, Douglas W., Citron, Martin, Biere, Anja-Leona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352257/ https://www.ncbi.nlm.nih.gov/pubmed/37460603 http://dx.doi.org/10.1038/s41531-023-00552-7

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