Lysine butyrylation of HSP90 regulated by KAT8 and HDAC11 confers chemoresistance

Posttranslational modification dramatically enhances protein complexity, but the function and precise mechanism of novel lysine acylation modifications remain unknown. Chemoresistance remains a daunting challenge to successful treatment. We found that lysine butyrylation (Kbu) is specifically upregu...

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Detalles Bibliográficos
Autores principales: He, Yan, Zheng, Can-Can, Yang, Jing, Li, Shu-Jun, Xu, Tao-Yang, Wei, Xian, Chen, Wen-You, Jiang, Zhi-Li, Xu, Jiao-Jiao, Zhang, Guo-Geng, Cheng, Chao, Chen, Kui-Sheng, Shi, Xing-Yuan, Qin, Da-Jiang, Liu, Jin-Bao, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352258/
https://www.ncbi.nlm.nih.gov/pubmed/37460462
http://dx.doi.org/10.1038/s41421-023-00570-y

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