The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease

Multiple myeloma bone disease is characterized by the development of osteolytic bone lesions. Recent work identified matrix metalloproteinase 13 as a myeloma-derived fusogen that induces osteoclast activation independent of its proteolytic activity. We now identify programmed death-1 homolog, PD-1H,...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Jing, Li, Shirong, Ma, Huihui, Yang, Jun, Pagnotti, Gabriel M., Brown, Lewis M., Weiss, Stephen J., Mapara, Markus Y., Lentzsch, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352288/
https://www.ncbi.nlm.nih.gov/pubmed/37460553
http://dx.doi.org/10.1038/s41467-023-39769-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352288/
https://www.ncbi.nlm.nih.gov/pubmed/37460553
http://dx.doi.org/10.1038/s41467-023-39769-8

Ejemplares similares