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Molecular basis of β-lactam antibiotic resistance of ESKAPE bacterium E. faecium Penicillin Binding Protein PBP5

Penicillin-binding proteins (PBPs) are essential for the formation of the bacterial cell wall. They are also the targets of β-lactam antibiotics. In Enterococcus faecium, high levels of resistance to β-lactams are associated with the expression of PBP5, with higher levels of resistance associated wi...

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Detalles Bibliográficos
Autores principales: Hunashal, Yamanappa, Kumar, Ganesan Senthil, Choy, Meng S., D’Andréa, Éverton D., Da Silva Santiago, Andre, Schoenle, Marta V., Desbonnet, Charlene, Arthur, Michel, Rice, Louis B., Page, Rebecca, Peti, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352307/
https://www.ncbi.nlm.nih.gov/pubmed/37460557
http://dx.doi.org/10.1038/s41467-023-39966-5