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Epigenetic mechanisms to propagate histone acetylation by p300/CBP

Histone acetylation is important for the activation of gene transcription but little is known about its direct read/write mechanisms. Here, we report cryogenic electron microscopy structures in which a p300/CREB-binding protein (CBP) multidomain monomer recognizes histone H4 N-terminal tail (NT) ace...

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Detalles Bibliográficos
Autores principales:	Kikuchi, Masaki, Morita, Satoshi, Wakamori, Masatoshi, Sato, Shin, Uchikubo-Kamo, Tomomi, Suzuki, Takehiro, Dohmae, Naoshi, Shirouzu, Mikako, Umehara, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352329/ https://www.ncbi.nlm.nih.gov/pubmed/37460559 http://dx.doi.org/10.1038/s41467-023-39735-4

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