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Impaired T-cell response to phytohemagglutinin (PHA) in tuberculosis patients is associated with high IL-6 plasma levels and normalizes early during anti-mycobacterial treatment

PURPOSE: Human tuberculosis is characterized by immunopathology that affects T-cell phenotype and functions. Previous studies found impaired T-cell response to phytohemagglutinin (PHA) in patients with acute tuberculosis. However, the influence of disease severity, affected T-cell subsets, and under...

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Detalles Bibliográficos
Autores principales: Vivekanandan, Monika M., Adankwah, Ernest, Aniagyei, Wilfred, Acheampong, Isaac, Minadzi, Difery, Yeboah, Augustine, Arthur, Joseph F., Lamptey, Millicent, Abass, Mohammed K., Kumbel, Francis, Osei-Yeboah, Francis, Gawusu, Amidu, Debrah, Linda Batsa, Owusu, Dorcas O., Debrah, Alexander, Mayatepek, Ertan, Seyfarth, Julia, Phillips, Richard O., Jacobsen, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352402/
https://www.ncbi.nlm.nih.gov/pubmed/36650358
http://dx.doi.org/10.1007/s15010-023-01977-1