Cargando…
F-ATP synthase inhibitory factor 1 regulates metabolic reprogramming involving its interaction with c-Myc and PGC1α
F-ATP synthase inhibitory factor 1 (IF1) is an intrinsic inhibitor of F-ATP synthase. It is known that IF1 mediates metabolic phenotypes and cell fate, yet the molecular mechanisms through which IF1 fulfills its physiological functions are not fully understood. Ablation of IF1 favors metabolic switc...
Autores principales: | Guo, Lishu, Gu, Zhenglong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352482/ https://www.ncbi.nlm.nih.gov/pubmed/37469400 http://dx.doi.org/10.3389/fonc.2023.1207603 |
Ejemplares similares
-
Mitochondrial ATP synthase inhibitory factor 1 interacts with the p53–cyclophilin D complex and promotes opening of the permeability transition pore
por: Guo, Lishu
Publicado: (2022) -
Deciphering the Dichotomous Effects of PGC-1α on Tumorigenesis and Metastasis
por: Gravel, Simon-Pierre
Publicado: (2018) -
The C Ring of the F1Fo ATP Synthase Forms the Mitochondrial Permeability Transition Pore: A Critical Appraisal
por: Halestrap, Andrew P.
Publicado: (2014) -
Knockdown of PGC1α suppresses dysplastic oral keratinocytes proliferation through reprogramming energy metabolism
por: Liu, Yunkun, et al.
Publicado: (2023) -
Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pulmonary fibrosis
por: Gu, Linlin, et al.
Publicado: (2019)