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Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging
Macrophages adapt distinct pro‐inflammatory (M1‐like) and pro‐resolving (M2‐like) phenotypes with specific tasks in the immune response and tissue homeostasis. Altered macrophage responses with age are causative for unresolved inflammation, so‐called inflammaging, and lead to higher infection suscep...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352559/ https://www.ncbi.nlm.nih.gov/pubmed/37101405 http://dx.doi.org/10.1111/acel.13856 |