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Spatial resolution of cellular senescence dynamics in human colorectal liver metastasis

Hepatic metastasis is a clinical challenge for colorectal cancer (CRC). Senescent cancer cells accumulate in CRC favoring tumor dissemination. Whether this mechanism progresses also in metastasis is unexplored. Here, we integrated spatial transcriptomics, 3D‐microscopy, and multicellular transcripto...

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Detalles Bibliográficos
Autores principales:	Garbarino, Ombretta, Lambroia, Luca, Basso, Gianluca, Marrella, Veronica, Franceschini, Barbara, Soldani, Cristiana, Pasqualini, Fabio, Giuliano, Desiree, Costa, Guido, Peano, Clelia, Barbarossa, Davide, Annarita, Destro, Salvati, Andreina, Terracciano, Luigi, Torzilli, Guido, Donadon, Matteo, Faggioli, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352575/ https://www.ncbi.nlm.nih.gov/pubmed/37157887 http://dx.doi.org/10.1111/acel.13853

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