O-GlcNAcylation regulates extracellular signal-regulated kinase (ERK) activation in Alzheimer’s disease

INTRODUCTION: Aberrant activation of Extracellular Signal-Regulated Kinase (ERK) signaling is associated with Alzheimer’s disease (AD) pathogenesis. For example, enhanced ERK signal activation mediated by Apolipoprotein E4 (APOE4), which is a critical genetic risk factor for AD, increases the transc...

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Detalles Bibliográficos
Autores principales: Ephrame, Sophiya John, Cork, Gentry K., Marshall, Victoria, Johnston, Margaret A., Shawa, Jenna, Alghusen, Ibtihal, Qiang, Amy, Denson, Aspin R., Carman, Marisa S., Fedosyuk, Halyna, Swerdlow, Russell H., Slawson, Chad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352608/
https://www.ncbi.nlm.nih.gov/pubmed/37469955
http://dx.doi.org/10.3389/fnagi.2023.1155630

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