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gtAI: an improved species-specific tRNA adaptation index using the genetic algorithm

The tRNA adaptation index (tAI) is a translation efficiency metric that considers weighted values (S ( ij ) values) for codon–tRNA wobble interaction efficiencies. The initial implementation of the tAI had significant flaws. For instance, generated S ( ij ) weights were optimized based on gene expre...

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Detalles Bibliográficos
Autores principales:	Anwar, Ali Mostafa, Khodary, Saif M., Ahmed, Eman Ali, Osama, Aya, Ezzeldin, Shahd, Tanios, Anthony, Mahgoub, Sebaey, Magdeldin, Sameh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352787/ https://www.ncbi.nlm.nih.gov/pubmed/37469707 http://dx.doi.org/10.3389/fmolb.2023.1218518

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