Herbal medicine and its impact on the gut microbiota in colorectal cancer

It is well-established that there are trillions of gut microbiota (GM) in the human gut. GM and its metabolites can reportedly cause cancer by causing abnormal immune responses. With the development of sequencing technology and the application of germ-free models in recent years, significant inroads...

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Autores principales: Bu, Fan, Tu, Yifeng, Wan, Ziang, Tu, Shiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352802/
https://www.ncbi.nlm.nih.gov/pubmed/37469598
http://dx.doi.org/10.3389/fcimb.2023.1096008
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author Bu, Fan
Tu, Yifeng
Wan, Ziang
Tu, Shiliang
author_facet Bu, Fan
Tu, Yifeng
Wan, Ziang
Tu, Shiliang
author_sort Bu, Fan
collection PubMed
description It is well-established that there are trillions of gut microbiota (GM) in the human gut. GM and its metabolites can reportedly cause cancer by causing abnormal immune responses. With the development of sequencing technology and the application of germ-free models in recent years, significant inroads have been achieved in research on GM and microbiota-related metabolites. Accordingly, the role and mechanism of GM in colorectal cancer (CRC) development have been gradually revealed. Traditional Chinese medicine (TCM) represents an important source of natural medicines and herbal products, with huge potential as anti-CRC agents. The potential application of TCM to target gut microbes for the treatment of colorectal cancer represents an exciting area of investigation.
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spelling pubmed-103528022023-07-19 Herbal medicine and its impact on the gut microbiota in colorectal cancer Bu, Fan Tu, Yifeng Wan, Ziang Tu, Shiliang Front Cell Infect Microbiol Cellular and Infection Microbiology It is well-established that there are trillions of gut microbiota (GM) in the human gut. GM and its metabolites can reportedly cause cancer by causing abnormal immune responses. With the development of sequencing technology and the application of germ-free models in recent years, significant inroads have been achieved in research on GM and microbiota-related metabolites. Accordingly, the role and mechanism of GM in colorectal cancer (CRC) development have been gradually revealed. Traditional Chinese medicine (TCM) represents an important source of natural medicines and herbal products, with huge potential as anti-CRC agents. The potential application of TCM to target gut microbes for the treatment of colorectal cancer represents an exciting area of investigation. Frontiers Media S.A. 2023-07-04 /pmc/articles/PMC10352802/ /pubmed/37469598 http://dx.doi.org/10.3389/fcimb.2023.1096008 Text en Copyright © 2023 Bu, Tu, Wan and Tu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Bu, Fan
Tu, Yifeng
Wan, Ziang
Tu, Shiliang
Herbal medicine and its impact on the gut microbiota in colorectal cancer
title Herbal medicine and its impact on the gut microbiota in colorectal cancer
title_full Herbal medicine and its impact on the gut microbiota in colorectal cancer
title_fullStr Herbal medicine and its impact on the gut microbiota in colorectal cancer
title_full_unstemmed Herbal medicine and its impact on the gut microbiota in colorectal cancer
title_short Herbal medicine and its impact on the gut microbiota in colorectal cancer
title_sort herbal medicine and its impact on the gut microbiota in colorectal cancer
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352802/
https://www.ncbi.nlm.nih.gov/pubmed/37469598
http://dx.doi.org/10.3389/fcimb.2023.1096008
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AT tushiliang herbalmedicineanditsimpactonthegutmicrobiotaincolorectalcancer

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