A rat model of metabolic syndrome-related heart failure with preserved ejection fraction phenotype: pathological alterations and possible molecular mechanisms

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) represents a syndrome involving multiple pathophysiologic disorders and clinical phenotypes. This complexity makes it challenging to develop a comprehensive preclinical model, which presents an obstacle to elucidating disease mechani...

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Detalles Bibliográficos
Autores principales: Shi, Yujiao, Liu, Chunqiu, Yang, Chenguang, Qiao, Wenbo, Liu, Yongcheng, Liu, Siyu, Dong, GuoJu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352810/
https://www.ncbi.nlm.nih.gov/pubmed/37469482
http://dx.doi.org/10.3389/fcvm.2023.1208370

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