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Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study

INTRODUCTION: Adolescence is marked by physiological and social changes, such as puberty, increased responsibilities and earlier school start times. This often leads to insufficient sleep on school nights and the need to compensate for lost sleep on weekends, causing a misalignment between biologica...

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Autores principales: Pompeia, Sabine, Panjeh, Sareh, Louzada, Fernando Mazzili, D’Almeida, Vania, Hipolide, Debora Cristina, Cogo-Moreira, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352840/
https://www.ncbi.nlm.nih.gov/pubmed/37469985
http://dx.doi.org/10.3389/fendo.2023.1085302
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author Pompeia, Sabine
Panjeh, Sareh
Louzada, Fernando Mazzili
D’Almeida, Vania
Hipolide, Debora Cristina
Cogo-Moreira, Hugo
author_facet Pompeia, Sabine
Panjeh, Sareh
Louzada, Fernando Mazzili
D’Almeida, Vania
Hipolide, Debora Cristina
Cogo-Moreira, Hugo
author_sort Pompeia, Sabine
collection PubMed
description INTRODUCTION: Adolescence is marked by physiological and social changes, such as puberty, increased responsibilities and earlier school start times. This often leads to insufficient sleep on school nights and the need to compensate for lost sleep on weekends, causing a misalignment between biological and social times, which has been termed social jetlag (SJL). SJL triggers stress responses and is associated with several negative health outcomes, including higher cardiometabolic risk in adults. In adolescence, however, SJL has only been consistently related to increases in adiposity but its association with other cardiometabolic indicators are unclear. METHOD: In a sample of 278 healthy early adolescents (9-15 years of age; 168 girls) we investigated: 1) whether self-reported SJL is associated (using path analyses) with a cardiometabolic status latent factor obtained by testing the best fitting model via confirmatory factor analyses from an initial set of eight indicators [body mass index (BMI), waist/height ratio, triglyceride concentration, diastolic and systolic blood pressure, glycated hemoglobin, total cholesterol/high-density lipoprotein ratio (chol/HDL), and % body fat]; and 2) whether age and/or pubertal status influence the association between SJL and cardiometabolic status. RESULT: We found that, for girls, higher SJL was associated with more adverse cardiometabolic latent scores (the shared variance of BMI, waist/height ratio, chol/HDL and systolic blood pressure, which had acceptable model fit indices). However, the role of age and pubertal status in this association was unclear for both sexes. DISCUSSION: SJL was associated with adverse cardiometabolic latent traits beyond increases in adiposity in this observational study in early female adolescents. Because disruptions of circadian rhythms are believed to lead to dysregulated energy homeostasis and not vice-versa, our findings highlight the need for sleep interventions in adolescence to help reduce the global burden of cardiometabolic ill health, especially in girls.
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spelling pubmed-103528402023-07-19 Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study Pompeia, Sabine Panjeh, Sareh Louzada, Fernando Mazzili D’Almeida, Vania Hipolide, Debora Cristina Cogo-Moreira, Hugo Front Endocrinol (Lausanne) Endocrinology INTRODUCTION: Adolescence is marked by physiological and social changes, such as puberty, increased responsibilities and earlier school start times. This often leads to insufficient sleep on school nights and the need to compensate for lost sleep on weekends, causing a misalignment between biological and social times, which has been termed social jetlag (SJL). SJL triggers stress responses and is associated with several negative health outcomes, including higher cardiometabolic risk in adults. In adolescence, however, SJL has only been consistently related to increases in adiposity but its association with other cardiometabolic indicators are unclear. METHOD: In a sample of 278 healthy early adolescents (9-15 years of age; 168 girls) we investigated: 1) whether self-reported SJL is associated (using path analyses) with a cardiometabolic status latent factor obtained by testing the best fitting model via confirmatory factor analyses from an initial set of eight indicators [body mass index (BMI), waist/height ratio, triglyceride concentration, diastolic and systolic blood pressure, glycated hemoglobin, total cholesterol/high-density lipoprotein ratio (chol/HDL), and % body fat]; and 2) whether age and/or pubertal status influence the association between SJL and cardiometabolic status. RESULT: We found that, for girls, higher SJL was associated with more adverse cardiometabolic latent scores (the shared variance of BMI, waist/height ratio, chol/HDL and systolic blood pressure, which had acceptable model fit indices). However, the role of age and pubertal status in this association was unclear for both sexes. DISCUSSION: SJL was associated with adverse cardiometabolic latent traits beyond increases in adiposity in this observational study in early female adolescents. Because disruptions of circadian rhythms are believed to lead to dysregulated energy homeostasis and not vice-versa, our findings highlight the need for sleep interventions in adolescence to help reduce the global burden of cardiometabolic ill health, especially in girls. Frontiers Media S.A. 2023-07-04 /pmc/articles/PMC10352840/ /pubmed/37469985 http://dx.doi.org/10.3389/fendo.2023.1085302 Text en Copyright © 2023 Pompeia, Panjeh, Louzada, D’Almeida, Hipolide and Cogo-Moreira https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Pompeia, Sabine
Panjeh, Sareh
Louzada, Fernando Mazzili
D’Almeida, Vania
Hipolide, Debora Cristina
Cogo-Moreira, Hugo
Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study
title Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study
title_full Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study
title_fullStr Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study
title_full_unstemmed Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study
title_short Social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study
title_sort social jetlag is associated with adverse cardiometabolic latent traits in early adolescence: an observational study
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352840/
https://www.ncbi.nlm.nih.gov/pubmed/37469985
http://dx.doi.org/10.3389/fendo.2023.1085302
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