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Inhibition of TANK‐binding kinase1 attenuates the astrocyte‐mediated neuroinflammatory response through YAP signaling after spinal cord injury

AIMS: TANK‐binding kinase 1 (TBK1) is involved in regulating the pathological process of a variety of inflammatory diseases in the central nervous system. However, its role and underlying molecular mechanisms in spinal cord injury (SCI) remain largely unknown. METHODS: We employed the TBK1 inhibitor...

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Detalles Bibliográficos
Autores principales: Zhang, Wenbin, Jia, Mengxian, Lian, Jiashu, Lu, Sheng, Zhou, Jian, Fan, Ziwei, Zhu, Zhoule, He, Yaozhi, Huang, Changgang, Zhu, Mingyu, Wang, Jian, Wang, Ying, Huang, Zhihui, Teng, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352897/
https://www.ncbi.nlm.nih.gov/pubmed/37032635
http://dx.doi.org/10.1111/cns.14170

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