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Computational pharmacogenotype extraction from clinical next-generation sequencing

BACKGROUND: Next-generation sequencing (NGS), including whole genome sequencing (WGS) and whole exome sequencing (WES), is increasingly being used for clinic care. While NGS data have the potential to be repurposed to support clinical pharmacogenomics (PGx), current computational approaches have not...

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Detalles Bibliográficos
Autores principales: Shugg, Tyler, Ly, Reynold C., Osei, Wilberforce, Rowe, Elizabeth J., Granfield, Caitlin A., Lynnes, Ty C., Medeiros, Elizabeth B., Hodge, Jennelle C., Breman, Amy M., Schneider, Bryan P., Sahinalp, S. Cenk, Numanagić, Ibrahim, Salisbury, Benjamin A., Bray, Steven M., Ratcliff, Ryan, Skaar, Todd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352904/
https://www.ncbi.nlm.nih.gov/pubmed/37469403
http://dx.doi.org/10.3389/fonc.2023.1199741

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