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IRF4 is required for migration of CD4(+) T cells to the intestine but not for Th2 and Th17 cell maintenance
The transcription factor Interferon Regulatory Factor 4 (IRF4) is central in control of T cell activation and differentiation. Deficiency of IRF4 results in severe immune deficiency and affects maturation and function of most if not all T cell subsets. Here we use mouse infection models for Citrobac...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352983/ https://www.ncbi.nlm.nih.gov/pubmed/37469513 http://dx.doi.org/10.3389/fimmu.2023.1182502 |