IRF4 is required for migration of CD4(+) T cells to the intestine but not for Th2 and Th17 cell maintenance

The transcription factor Interferon Regulatory Factor 4 (IRF4) is central in control of T cell activation and differentiation. Deficiency of IRF4 results in severe immune deficiency and affects maturation and function of most if not all T cell subsets. Here we use mouse infection models for Citrobac...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Constantin, Harberts, Aenne, Reimers, Daniel, Bertram, Tabea, Voß, Leonie Caroline, Schmid, Joanna, Lory, Niels Christian, Spohn, Michael, Koch-Nolte, Friedrich, Huber, Samuel, Raczkowski, Friederike, Breloer, Minka, Mittrücker, Hans-Willi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352983/
https://www.ncbi.nlm.nih.gov/pubmed/37469513
http://dx.doi.org/10.3389/fimmu.2023.1182502

Ejemplares similares

Ejemplares similares