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The landscape of PBMC methylome in canine mammary tumors reveals the epigenetic regulation of immune marker genes and its potential application in predicting tumor malignancy

BACKGROUND: Genome-wide dysregulation of CpG methylation accompanies tumor progression and characteristic states of cancer cells, prompting a rationale for biomarker development. Understanding how the archetypic epigenetic modification determines systemic contributions of immune cell types is the ke...

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Detalles Bibliográficos
Autores principales: Nam, A-Reum, Heo, Min, Lee, Kang-Hoon, Kim, Ji-Yoon, Won, Sung-Ho, Cho, Je-Yoel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353108/
https://www.ncbi.nlm.nih.gov/pubmed/37460953
http://dx.doi.org/10.1186/s12864-023-09471-6

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