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Bifidobacterium adolescentis induces Decorin(+) macrophages via TLR2 to suppress colorectal carcinogenesis

BACKGROUND: The interplay between gut microbiota and tumor microenvironment (TME) in the pathogenesis of colorectal cancer (CRC) is largely unknown. Here, we elucidated the functional role of B. adolescentis and its possible mechanism on the manipulation of Decorin(+) macrophages in colorectal cance...

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Detalles Bibliográficos
Autores principales: Lin, Yifeng, Fan, Lina, Qi, Yadong, Xu, Chaochao, Jia, Dingjiacheng, Jiang, Yao, Chen, Shujie, Wang, Liangjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353206/
https://www.ncbi.nlm.nih.gov/pubmed/37464382
http://dx.doi.org/10.1186/s13046-023-02746-6