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Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus

Diabetes can lead to various acute clinical complications, although the occurrence of ophthalmic signs and symptoms is uncommon. Neovascular glaucoma (NG), a rare complication associated with diabetes mellitus, is one such condition. Additionally, anti-vascular endothelial growth factor (VEGF)-induc...

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Autores principales: Barkhane, Zineb, Qureshi, Maria, Jamil, Ahmed, Chowdhury, Purnashree, Kamran, Muhammad, Altayb Ismail, Mohamedalamin Alnoor, Saeed, Shahzeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353264/
https://www.ncbi.nlm.nih.gov/pubmed/37469817
http://dx.doi.org/10.7759/cureus.40584
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author Barkhane, Zineb
Qureshi, Maria
Jamil, Ahmed
Chowdhury, Purnashree
Kamran, Muhammad
Altayb Ismail, Mohamedalamin Alnoor
Saeed, Shahzeb
author_facet Barkhane, Zineb
Qureshi, Maria
Jamil, Ahmed
Chowdhury, Purnashree
Kamran, Muhammad
Altayb Ismail, Mohamedalamin Alnoor
Saeed, Shahzeb
author_sort Barkhane, Zineb
collection PubMed
description Diabetes can lead to various acute clinical complications, although the occurrence of ophthalmic signs and symptoms is uncommon. Neovascular glaucoma (NG), a rare complication associated with diabetes mellitus, is one such condition. Additionally, anti-vascular endothelial growth factor (VEGF)-induced toxic anterior segment syndrome (TASS) is a rare complication of intravitreal bevacizumab. In this case report, we present a unique case of a patient with juvenile diabetes (type 1 diabetes mellitus) who presented to the emergency room (ER) with typical features of diabetic ketoacidosis (DKA) accompanied by bilateral ocular pain. Subsequent investigation revealed secondary angle-closure neovascular glaucoma as the underlying cause. The patient received management for DKA in the ER and subsequent medicine ward. Various interventions were performed for glaucoma in the right eye, including addressing cataracts, which ultimately resulted in TASS. The patient was successfully treated with cryo-diode laser therapy.
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spelling pubmed-103532642023-07-19 Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus Barkhane, Zineb Qureshi, Maria Jamil, Ahmed Chowdhury, Purnashree Kamran, Muhammad Altayb Ismail, Mohamedalamin Alnoor Saeed, Shahzeb Cureus Endocrinology/Diabetes/Metabolism Diabetes can lead to various acute clinical complications, although the occurrence of ophthalmic signs and symptoms is uncommon. Neovascular glaucoma (NG), a rare complication associated with diabetes mellitus, is one such condition. Additionally, anti-vascular endothelial growth factor (VEGF)-induced toxic anterior segment syndrome (TASS) is a rare complication of intravitreal bevacizumab. In this case report, we present a unique case of a patient with juvenile diabetes (type 1 diabetes mellitus) who presented to the emergency room (ER) with typical features of diabetic ketoacidosis (DKA) accompanied by bilateral ocular pain. Subsequent investigation revealed secondary angle-closure neovascular glaucoma as the underlying cause. The patient received management for DKA in the ER and subsequent medicine ward. Various interventions were performed for glaucoma in the right eye, including addressing cataracts, which ultimately resulted in TASS. The patient was successfully treated with cryo-diode laser therapy. Cureus 2023-06-18 /pmc/articles/PMC10353264/ /pubmed/37469817 http://dx.doi.org/10.7759/cureus.40584 Text en Copyright © 2023, Barkhane et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Barkhane, Zineb
Qureshi, Maria
Jamil, Ahmed
Chowdhury, Purnashree
Kamran, Muhammad
Altayb Ismail, Mohamedalamin Alnoor
Saeed, Shahzeb
Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus
title Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus
title_full Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus
title_fullStr Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus
title_full_unstemmed Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus
title_short Murphy’s Law and Ophthalmic Complications in a Patient With Type 1 Diabetes Mellitus
title_sort murphy’s law and ophthalmic complications in a patient with type 1 diabetes mellitus
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353264/
https://www.ncbi.nlm.nih.gov/pubmed/37469817
http://dx.doi.org/10.7759/cureus.40584
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