Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions

The bacterial pathogen Klebsiella pneumoniae causes nosocomial infections with the acquisition of multidrug resistance, impeding treatment options. This study investigated the effect of zinc limitation on the phosphoproteome of K. pneumoniae using quantitative mass spectrometry. New insight is provi...

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Detalles Bibliográficos
Autores principales: Reitzel, Chelsea, Sukumaran, Arjun, Zanetti, Christina, Muselius, Benjamin, Geddes-McAlister, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Omics Data Sets
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353368/
https://www.ncbi.nlm.nih.gov/pubmed/37358435
http://dx.doi.org/10.1128/mra.00258-23
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author Reitzel, Chelsea
Sukumaran, Arjun
Zanetti, Christina
Muselius, Benjamin
Geddes-McAlister, Jennifer
author_facet Reitzel, Chelsea
Sukumaran, Arjun
Zanetti, Christina
Muselius, Benjamin
Geddes-McAlister, Jennifer
author_sort Reitzel, Chelsea
collection PubMed
description The bacterial pathogen Klebsiella pneumoniae causes nosocomial infections with the acquisition of multidrug resistance, impeding treatment options. This study investigated the effect of zinc limitation on the phosphoproteome of K. pneumoniae using quantitative mass spectrometry. New insight is provided into cellular signaling methods used by the pathogen to respond to nutrient-limited environments.
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spelling pubmed-103533682023-07-19 Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions Reitzel, Chelsea Sukumaran, Arjun Zanetti, Christina Muselius, Benjamin Geddes-McAlister, Jennifer Microbiol Resour Announc Omics Data Sets The bacterial pathogen Klebsiella pneumoniae causes nosocomial infections with the acquisition of multidrug resistance, impeding treatment options. This study investigated the effect of zinc limitation on the phosphoproteome of K. pneumoniae using quantitative mass spectrometry. New insight is provided into cellular signaling methods used by the pathogen to respond to nutrient-limited environments. American Society for Microbiology 2023-06-26 /pmc/articles/PMC10353368/ /pubmed/37358435 http://dx.doi.org/10.1128/mra.00258-23 Text en Copyright © 2023 Reitzel et al. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Omics Data Sets
Reitzel, Chelsea
Sukumaran, Arjun
Zanetti, Christina
Muselius, Benjamin
Geddes-McAlister, Jennifer
Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions
title Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions
title_full Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions
title_fullStr Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions
title_full_unstemmed Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions
title_short Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions
title_sort phosphoproteome profiling of klebsiella pneumoniae under zinc-limited and zinc-replete conditions
topic Omics Data Sets
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353368/
https://www.ncbi.nlm.nih.gov/pubmed/37358435
http://dx.doi.org/10.1128/mra.00258-23
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