Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab

The emergence of the Omicron variant of SARS-CoV-2 represented a challenge to the treatment of COVID-19 using monoclonal antibodies. Only Sotrovimab maintained partial activity, allowing it to be used in high-risk patients infected with the Omicron variant. However, reports of resistance mutations t...

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Detalles Bibliográficos
Autores principales: Palomino-Cabrera, Rosalía, Tejerina, Francisco, Molero-Salinas, Andrea, Ferris, María, Veintimilla, Cristina, Catalán, Pilar, Rodríguez Macias, Gabriela, Alonso, Roberto, Muñoz, Patricia, García de Viedma, Darío, Pérez-Lago, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353472/
https://www.ncbi.nlm.nih.gov/pubmed/37278655
http://dx.doi.org/10.1128/aac.00266-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353472/
https://www.ncbi.nlm.nih.gov/pubmed/37278655
http://dx.doi.org/10.1128/aac.00266-23

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