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Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report

BACKGROUND: Colon cancer (CC) is one of the leading causes of cancer-related morbidity and mortality worldwide. Traditional Chinese medicine (TCM) is widely used in the treatment of various chronic diseases. CC easily metastasizes and results in high morbidity and mortality rates. CASE SUMMARY: A 71...

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Autores principales: Deng, Chen-Geng, Tang, Meng-Yuan, Pan, Xue, Liu, Zhao-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353496/
https://www.ncbi.nlm.nih.gov/pubmed/37469725
http://dx.doi.org/10.12998/wjcc.v11.i19.4670
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author Deng, Chen-Geng
Tang, Meng-Yuan
Pan, Xue
Liu, Zhao-Heng
author_facet Deng, Chen-Geng
Tang, Meng-Yuan
Pan, Xue
Liu, Zhao-Heng
author_sort Deng, Chen-Geng
collection PubMed
description BACKGROUND: Colon cancer (CC) is one of the leading causes of cancer-related morbidity and mortality worldwide. Traditional Chinese medicine (TCM) is widely used in the treatment of various chronic diseases. CC easily metastasizes and results in high morbidity and mortality rates. CASE SUMMARY: A 71-year-old man with a 12-year history of old myocardial infarction and a 7-year history of type 2 diabetes mellitus was diagnosed with CC and underwent right hemicolectomy 1 year ago. Tumor biopsy revealed moderately poorly differentiated adenocarcinoma. Subsequently, chemotherapy with oxaliplatin and paclitaxel was administered. Anastomosis recurrence and pelvic metastasis were noted 37 d later. The patient received eight 21-d cycles of adjuvant chemotherapy with oxaliplatin and capecitabine after recurrence. However, the tumor persisted, and chemotherapy-related liver damage developed gradually. Thus, he was advised to take TCM for the recurrence and pelvic metastasis. The patient’s metastatic CC was cured after receiving TCM combined with long-term chemotherapy. CONCLUSION: TCM may be an effective adjunct therapy in the treatment of patients with metastatic CC.
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spelling pubmed-103534962023-07-19 Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report Deng, Chen-Geng Tang, Meng-Yuan Pan, Xue Liu, Zhao-Heng World J Clin Cases Case Report BACKGROUND: Colon cancer (CC) is one of the leading causes of cancer-related morbidity and mortality worldwide. Traditional Chinese medicine (TCM) is widely used in the treatment of various chronic diseases. CC easily metastasizes and results in high morbidity and mortality rates. CASE SUMMARY: A 71-year-old man with a 12-year history of old myocardial infarction and a 7-year history of type 2 diabetes mellitus was diagnosed with CC and underwent right hemicolectomy 1 year ago. Tumor biopsy revealed moderately poorly differentiated adenocarcinoma. Subsequently, chemotherapy with oxaliplatin and paclitaxel was administered. Anastomosis recurrence and pelvic metastasis were noted 37 d later. The patient received eight 21-d cycles of adjuvant chemotherapy with oxaliplatin and capecitabine after recurrence. However, the tumor persisted, and chemotherapy-related liver damage developed gradually. Thus, he was advised to take TCM for the recurrence and pelvic metastasis. The patient’s metastatic CC was cured after receiving TCM combined with long-term chemotherapy. CONCLUSION: TCM may be an effective adjunct therapy in the treatment of patients with metastatic CC. Baishideng Publishing Group Inc 2023-07-06 2023-07-06 /pmc/articles/PMC10353496/ /pubmed/37469725 http://dx.doi.org/10.12998/wjcc.v11.i19.4670 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Deng, Chen-Geng
Tang, Meng-Yuan
Pan, Xue
Liu, Zhao-Heng
Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report
title Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report
title_full Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report
title_fullStr Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report
title_full_unstemmed Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report
title_short Metastatic colon cancer treated using traditional Chinese medicine combined with chemotherapy: A case report
title_sort metastatic colon cancer treated using traditional chinese medicine combined with chemotherapy: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353496/
https://www.ncbi.nlm.nih.gov/pubmed/37469725
http://dx.doi.org/10.12998/wjcc.v11.i19.4670
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