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A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery

Here, we present a case of severe meningoencephalitis caused by combined infection with tick-borne encephalitis (TBE) and Lyme borreliosis (LB) in a 25-year-old woman in a rural area of Zhambyl region, Kazakhstan. She presented with fever, nausea, vomiting, weakness, sweating, severe headache, arthr...

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Autores principales: Ostapchuk, Yekaterina O., Dmitrovskiy, Andrey M., Pak, Elena A., Perfilyeva, Yuliya V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353647/
https://www.ncbi.nlm.nih.gov/pubmed/37469466
http://dx.doi.org/10.4103/jgid.jgid_76_22
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author Ostapchuk, Yekaterina O.
Dmitrovskiy, Andrey M.
Pak, Elena A.
Perfilyeva, Yuliya V.
author_facet Ostapchuk, Yekaterina O.
Dmitrovskiy, Andrey M.
Pak, Elena A.
Perfilyeva, Yuliya V.
author_sort Ostapchuk, Yekaterina O.
collection PubMed
description Here, we present a case of severe meningoencephalitis caused by combined infection with tick-borne encephalitis (TBE) and Lyme borreliosis (LB) in a 25-year-old woman in a rural area of Zhambyl region, Kazakhstan. She presented with fever, nausea, vomiting, weakness, sweating, severe headache, arthralgia, and malaise. The course of illness was further complicated by encephalitis with symmetric lesions of the midbrain cerebral peduncles and serous meningitis. TBE and LB co-infection were established by a two-fold increase in serum IgG titers between day 21 and day 25 of illness. Both infections responded well to combined therapy with human TBE immunoglobulins, antibiotics, antiviral drugs, glucocorticoids, and diuretics. The outcome of the disease was favorable and the patient recovered completely.
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spelling pubmed-103536472023-07-19 A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery Ostapchuk, Yekaterina O. Dmitrovskiy, Andrey M. Pak, Elena A. Perfilyeva, Yuliya V. J Glob Infect Dis Case Report Here, we present a case of severe meningoencephalitis caused by combined infection with tick-borne encephalitis (TBE) and Lyme borreliosis (LB) in a 25-year-old woman in a rural area of Zhambyl region, Kazakhstan. She presented with fever, nausea, vomiting, weakness, sweating, severe headache, arthralgia, and malaise. The course of illness was further complicated by encephalitis with symmetric lesions of the midbrain cerebral peduncles and serous meningitis. TBE and LB co-infection were established by a two-fold increase in serum IgG titers between day 21 and day 25 of illness. Both infections responded well to combined therapy with human TBE immunoglobulins, antibiotics, antiviral drugs, glucocorticoids, and diuretics. The outcome of the disease was favorable and the patient recovered completely. Wolters Kluwer - Medknow 2023-03-31 /pmc/articles/PMC10353647/ /pubmed/37469466 http://dx.doi.org/10.4103/jgid.jgid_76_22 Text en Copyright: © 2023 Journal of Global Infectious Diseases https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Ostapchuk, Yekaterina O.
Dmitrovskiy, Andrey M.
Pak, Elena A.
Perfilyeva, Yuliya V.
A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery
title A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery
title_full A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery
title_fullStr A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery
title_full_unstemmed A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery
title_short A Case of Combined Infection with Tick-Borne Encephalitis and Lyme Borreliosis with Severe Meningoencephalitis and Complete Recovery
title_sort case of combined infection with tick-borne encephalitis and lyme borreliosis with severe meningoencephalitis and complete recovery
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353647/
https://www.ncbi.nlm.nih.gov/pubmed/37469466
http://dx.doi.org/10.4103/jgid.jgid_76_22
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