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Optimal evaluation of energy yield and driving force in microbial metabolic pathway variants

This work presents a methodology to evaluate the bioenergetic feasibility of alternative metabolic pathways for a given microbial conversion, optimising their energy yield and driving forces as a function of the concentration of metabolic intermediates. The tool, based on thermodynamic principles an...

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Detalles Bibliográficos
Autores principales: Taha, Ahmed, Patón, Mauricio, Penas, David R., Banga, Julio R., Rodríguez, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353829/
https://www.ncbi.nlm.nih.gov/pubmed/37410779
http://dx.doi.org/10.1371/journal.pcbi.1011264