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Mechanism and therapeutic implications of pomalidomide-induced immune surface marker upregulation in EBV-positive lymphomas

Epstein-Barr virus (EBV) downregulates immune surface markers to avoid immune recognition. Pomalidomide (Pom) was previously shown to increase immune surface marker expression in EBV-infected tumor cells. We explored the mechanism by which Pom leads to these effects in EBV-infected cells. Pom increa...

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Detalles Bibliográficos
Autores principales: Jaeger, Hannah K., Davis, David A., Nair, Ashwin, Shrestha, Prabha, Stream, Alexandra, Yaparla, Amulya, Yarchoan, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354044/
https://www.ncbi.nlm.nih.gov/pubmed/37463943
http://dx.doi.org/10.1038/s41598-023-38156-z