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Activation of GABA(B) receptors in central amygdala attenuates activity of PKCδ + neurons and suppresses punishment-resistant alcohol self-administration in rats

Alcohol use despite negative consequences is a core phenomenon of alcohol addiction. We recently used alcohol self-administration that is resistant to footshock punishment as a model of this behavior, and found that activity of PKCδ + GABAergic neurons in the central amygdala (CeA) is a determinant...

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Detalles Bibliográficos
Autores principales: Domi, Esi, Xu, Li, Toivainen, Sanne, Wiskerke, Joost, Coppola, Andrea, Holm, Lovisa, Augier, Eric, Petrella, Michele, Heilig, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354045/
https://www.ncbi.nlm.nih.gov/pubmed/36739350
http://dx.doi.org/10.1038/s41386-023-01543-1