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Activation of GABA(B) receptors in central amygdala attenuates activity of PKCδ + neurons and suppresses punishment-resistant alcohol self-administration in rats
Alcohol use despite negative consequences is a core phenomenon of alcohol addiction. We recently used alcohol self-administration that is resistant to footshock punishment as a model of this behavior, and found that activity of PKCδ + GABAergic neurons in the central amygdala (CeA) is a determinant...
Autores principales: | Domi, Esi, Xu, Li, Toivainen, Sanne, Wiskerke, Joost, Coppola, Andrea, Holm, Lovisa, Augier, Eric, Petrella, Michele, Heilig, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354045/ https://www.ncbi.nlm.nih.gov/pubmed/36739350 http://dx.doi.org/10.1038/s41386-023-01543-1 |
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