Cryo-EM structure and polymorphic maturation of a viral transduction enhancing amyloid fibril

Amyloid fibrils have emerged as innovative tools to enhance the transduction efficiency of retroviral vectors in gene therapy strategies. In this study, we used cryo-electron microscopy to analyze the structure of a biotechnologically engineered peptide fibril that enhances retroviral infectivity. O...

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Detalles Bibliográficos
Autores principales: Heerde, Thomas, Schütz, Desiree, Lin, Yu-Jie, Münch, Jan, Schmidt, Matthias, Fändrich, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354054/
https://www.ncbi.nlm.nih.gov/pubmed/37464004
http://dx.doi.org/10.1038/s41467-023-40042-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354054/
https://www.ncbi.nlm.nih.gov/pubmed/37464004
http://dx.doi.org/10.1038/s41467-023-40042-1

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