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Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer

Non-melanoma skin cancer (NMSC) is the most common cancer in Caucasians worldwide. We investigated the pathophysiological role of MIF and its homolog D-DT in UVB- and chemically induced NMSC using Mif(−/−), D-dt(−/−) and Mif(−/−)/D-dt(−/−) mice on a hairless SKH1 background. Knockout of both cytokin...

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Detalles Bibliográficos
Autores principales: Huth, Sebastian, Huth, Laura, Heise, Ruth, Marquardt, Yvonne, Lopopolo, Linda, Piecychna, Marta, Boor, Peter, Fingerle-Rowson, Günter, Kapurniotu, Aphrodite, Yazdi, Amir S., Bucala, Richard, Bernhagen, Jürgen, Baron, Jens Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354066/
https://www.ncbi.nlm.nih.gov/pubmed/37464010
http://dx.doi.org/10.1038/s41598-023-38748-9