HCK induces macrophage activation to promote renal inflammation and fibrosis via suppression of autophagy

Renal inflammation and fibrosis are the common pathways leading to progressive chronic kidney disease (CKD). We previously identified hematopoietic cell kinase (HCK) as upregulated in human chronic allograft injury promoting kidney fibrosis; however, the cellular source and molecular mechanisms are...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Man, Menon, Madhav C., Wang, Wenlin, Fu, Jia, Yi, Zhengzi, Sun, Zeguo, Liu, Jessica, Li, Zhengzhe, Mou, Lingyun, Banu, Khadija, Lee, Sui-Wan, Dai, Ying, Anandakrishnan, Nanditha, Azeloglu, Evren U., Lee, Kyung, Zhang, Weijia, Das, Bhaskar, He, John Cijiang, Wei, Chengguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354075/
https://www.ncbi.nlm.nih.gov/pubmed/37463911
http://dx.doi.org/10.1038/s41467-023-40086-3

Ejemplares similares

Ejemplares similares