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Inhibition of dorsal raphe GABAergic neurons blocks hyperalgesia during heroin withdrawal
Opioid withdrawal signs, such as hyperalgesia, are manifestations of opioid use disorder that may contribute to opioid seeking and taking. We have previously identified an association between dorsal raphe (DR) neurons and the expression of hyperalgesia during spontaneous heroin withdrawal. Here, we...
Autores principales: | Alvarez-Bagnarol, Yocasta, García, Raul, Vendruscolo, Leandro F., Morales, Marisela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354084/ https://www.ncbi.nlm.nih.gov/pubmed/37270620 http://dx.doi.org/10.1038/s41386-023-01620-5 |
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