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Inhibition of dorsal raphe GABAergic neurons blocks hyperalgesia during heroin withdrawal

Opioid withdrawal signs, such as hyperalgesia, are manifestations of opioid use disorder that may contribute to opioid seeking and taking. We have previously identified an association between dorsal raphe (DR) neurons and the expression of hyperalgesia during spontaneous heroin withdrawal. Here, we...

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Detalles Bibliográficos
Autores principales: Alvarez-Bagnarol, Yocasta, García, Raul, Vendruscolo, Leandro F., Morales, Marisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354084/
https://www.ncbi.nlm.nih.gov/pubmed/37270620
http://dx.doi.org/10.1038/s41386-023-01620-5

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