Marine diterpenoid targets STING palmitoylation in mammalian cells

Natural products are important sources of therapeutic agents and useful drug discovery tools. The fused macrocycles and multiple stereocenters of briarane-type diterpenoids pose a major challenge to total synthesis and efforts to characterize their biological activities. Harnessing a scalable source...

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Detalles Bibliográficos
Autores principales: Hsiao, Wan-Chi, Niu, Guang-Hao, Lo, Chen-Fu, Wang, Jing-Ya, Chi, Ya-Hui, Huang, Wei-Cheng, Tung, Chun-Wei, Sung, Ping-Jyun, Tsou, Lun Kelvin, Zhang, Mingzi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354091/
https://www.ncbi.nlm.nih.gov/pubmed/37463995
http://dx.doi.org/10.1038/s42004-023-00956-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354091/
https://www.ncbi.nlm.nih.gov/pubmed/37463995
http://dx.doi.org/10.1038/s42004-023-00956-9

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