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Amphioxus adenosine-to-inosine tRNA-editing enzyme that can perform C-to-U and A-to-I deamination of DNA

Adenosine-to-inosine tRNA-editing enzyme has been identified for more than two decades, but the study on its DNA editing activity is rather scarce. We show that amphioxus (Branchiostoma japonicum) ADAT2 (BjADAT2) contains the active site ‘HxE-PCxxC’ and the key residues for target-base-binding, and...

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Detalles Bibliográficos
Autores principales:	Gao, Zhan, Jiang, Wanyue, Zhang, Yu, Zhang, Liping, Yi, Mengmeng, Wang, Haitao, Ma, Zengyu, Qu, Baozhen, Ji, Xiaohan, Long, Hongan, Zhang, Shicui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10354150/ https://www.ncbi.nlm.nih.gov/pubmed/37464027 http://dx.doi.org/10.1038/s42003-023-05134-0

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